401ab Medical Biochemistry (5, 3) Introduction to biochemistry emphasizing human and medical aspects, including the specific biochemistry of various human organ systems. Discussion groups in fall semester.
441 Biochemistry (4, Fa) Physical-chemical basis of life processes. Prerequisite: open to qualified students. (Danenberg, Kalra, Lee, Maxson, Stellwagen)
490x Directed Research (4) Designed to give undergraduate students a research opportunity with selected Biochemistry Department faculty. Students will work out details of the research with individual faculty members. Not available for credit to Biological Sciences majors. Prerequisite: BIOC 441 or BISC 216L.
501 Recent Advances in Biochemistry (2-4, max 16, Fa) Lectures on areas of intermediary metabolism and the chemistry of natural products. Prerequisite: BISC 435, CHEM 430ab.
502 Biochemistry Seminar (1, max 12, 2 years, Sp) Formal presentations and discussion by students of material from research literature. Corequisite: BISC 216L or BISC 434x.
503 Chemical Reaction Mechanisms in Biochemistry (4, 2 years, Fa) Mechanisms of reactions of interest in biochemistry from the standpoint of modern organic chemistry; hydrolytic and other reactions in aqueous systems and enzymatic reactions. Prerequisite: BISC 435, CHEM 430ab. (Fife)
505 Cofactor Catalyzed Reactions (2, 2 years, Fa) The mechanism of action of coenzymes such as pyridoxal, thiamin, NAD, tetrahydrofolic acid, etc.; their effects on enzymatic reactions, and the chemistry of related nonenzymatic reactions. Prerequisite: general biochemistry. (Fife)
506 Enzyme Kinetics and Mechanisms (2, 2 years, Sp) Theory and application of kinetic methods to the investigation of the mechanism of enzyme action. Prerequisite: general biochemistry. (Danenberg, Fife)
520 Membranes: Structures and Functions (2, 2 years, Sp) Current concepts of membranes; associated reactions; oxidative phosphorylation; transport of sugars, ions, amino acids, and conformational change. Prerequisite: general biochemistry. (Kalra, Levy)
525 Cellular Regulation of Metabolism (2, 2 years, Fa) Metabolic control of allosteric proteins; to include other regulatory phenomena such as genetic or hormonal control, or changes resulting from evolution or differentiation where appropriate. Prerequisite: BIOC 441. (Raijman)
530 Biochemistry of Anti-Cancer Agents (2, 2 years, Fa) Biochemical effects of antimetabolites, alkylating agents, vinca alkaloids, and other drugs on cancer cells. Detailed mechanisms of cytotoxicity and the emergence of drug resistance. Prerequisite: organic chemistry. (Danenberg, Moran)
536 Biochemistry of Cell-Cell Recognition (2, Irregular) Cell surface-related biochemical events during developmental stages; cell-cell communication through certain receptors; liposomes as models for cellular interactions. Prerequisite: one year general biochemistry. (Tokes)
542 Molecular Mechanisms of Gene Expression and Cellular Differentiation (4, 2 years, Sp) Nature of cellular differentiation; uses of cell culture systems; DNA sequence organization; RNA complexity; transcriptional and post-transcriptional control mechanisms in procaryotes and eucaryotes. Prerequisite: BIOC 441. (Jones, Lee, Maxson and Stellwagen)
551 Procaryotic Molecular Genetics (4, Fa) (Enroll in MICB 551)
561 Eucaryotic Gene Expression (4, Sp) DNA and RNA structure and function; biochemistry and molecular biology of replication, transcription, and translation in eucaryotic organisms; regulation of gene expression. Prerequisite: general biochemistry. (Stellwagen and others)
590 Directed Research (1-10, FaSpSm) Research leading to the master's degree. Maximum of 10 units may be applied to the degree upon approval of the department. There is no prerequisite.
594abz Master's Thesis (2-2-0, FaSpSm) Credit on acceptance of thesis. Graded IP/CR/NC.
599 Special Topics (2-4, max 8)
601 Molecular Biology of Gene Regulation (2, max 8, FaSp) Current techniques and systems in molecular biology from an interdisciplinary perspective: microbiological, biochemical, and pharmaceutical. Biochemistry candidates limited to two registrations.
602 Current Topics in Human Molecular Genetics (2) Current research in human genetics, including positional cloning of genes, mutational analysis of disease genes, construction and characterization of animal models, and gene therapy. Prerequisite: BIOC 551 and BIOC 561. (Reichardt, Anderson, Cortopassi)
790 Research (1-12, FaSpSm) Research leading to the doctorate. Maximum units which may be applied to the degree to be determined by the department. Graded CR/NC.
794abcdz Doctoral Dissertation (2-2-2-2-0, FaSpSm) Credit on acceptance of dissertation. Graded IP/CR/NC.
Produced by the USC Division of Student Affairs, Office of University Publications, May 1, 1995