Keck School of Medicine
Courses of Instruction
Interdepartmental (INTD)
The terms indicated are expected but are not guaranteed. For the courses offered during any given term, consult the Schedule of Classes.
INTD 500 Ethics and Accountability in Biomedical Research (1, Sm) The purpose of this course is to engage current (and potential) research trainees in discussions about the responsible conduct of science. The course is designed as an option for meeting current federal regulations which require that all predoctoral and postdoctoral fellows paid from federal contracts and grants have a component of ethical training. Graded CR/NC.
INTD 501 Recent Advances in Vision Science (1, max 4, FaSp) Recent advances in the understanding of the ocular surface are reported and discussed; students will learn how to read papers critically, develop speaking skills to explain a research paper and attend a three-day workshop on NIH proposal development and scientific manuscript preparation. Graded CR/NC.
INTD 504 Molecular Biology of Cancer (4, 2 years, Sp) Epidemiology, pathobiology, carcinogenesis, tumor biology and heterogeneity; retroviruses, oncogenes, cell cycle control, genetics of cancer, tumor immunology; treatment strategies.
INTD 522 Infection and Host Responses (4, Sp) Overview of microbes, their life cycles and the host response they elicit, evade or exploit, including the manipulation and the malfunction of the immune system.
INTD 531 Cell Biology (4, Fa) Current perspectives on major research areas in cell biology. Emphasis will be on in-depth examination of cellular structures, regulatory processes, intra-cellular routing and targeting, and cell/environmental interactions.
INTD 535 Continuing Introduction to Clinical Medicine for M.D./Ph.D. Students (1, FaSp) Course for M.D./Ph.D. students in Ph.D. years designed to allow maintenance and improvement of clinical skills prior to re-entry in clinical rotations in the Year III medical curriculum. Open only to medical students who have completed Years I and II. Graded CR/NC.
INTD 537 The Structure of Scientific Revolutions in Molecular Biology (1, Irregular) A course in how scientists make breakthrough discoveries and whether there are predictable ingredients for significant changes in perception of the living system. Open only to graduate-level students in any of the biological sciences. Recommended preparation: one year in cell and molecular biology.
INTD 549 Protein Chemistry — Structure and Function (4, Sp) Chemistry of peptides and proteins; protein structure and folding; molecular basis of protein action. (Duplicates credit in former BIOC 549.) Prerequisite: general biochemistry.
INTD 550 Introduction to Pathology (4, Fa) Normal histology and introduction to basic pathological concepts. Provides a solid and basic understanding of normal structures and how they relate to function.
INTD 551 Pathobiology of Disease (4, Sp) Relationship between histopathological and clinical manifestations of disease and their underlying molecular mechanisms. Topics include inflammatory, developmental, environmental, degenerative, and neoplastic disease processes. Prerequisite: INTD 550.
INTD 555 Biochemical and Molecular Bases of Disease (4) Biochemical and molecular abnormalities in disease states. Prerequisite: general biochemistry.
INTD 561 Molecular Biology (4, Fa) Biochemistry and molecular biology of replication, transcription, RNA processing, translation, and regulation of gene expression with emphasis on multicellular eukaryotic organisms and comparisons to prokaryotes.
INTD 567 Molecular and Cellular Neurobiology (4) (Enroll in NEUR 531)
INTD 571 Biochemistry (4, Sp) Physical-chemical basis of life processes: protein structure and enzyme function; synthesis and metabolism of carbohydrates, lipids, amino acids, and nucleotides. (Duplicates credit in former BIOC 441.) Prerequisite: open to qualified students.
INTD 572 Systems Physiology and Disease I (4, Fa) Mammalian organ systems operation during health, and pathophysiologic analysis of related diseases with focus on muscle, respiratory, cardiovascular and renal systems. Faculty from basic and clinical sciences. Open to graduate students in biomedical science only.
INTD 573 Systems Physiology and Disease II (4, Sp) Mammalian organ systems operation during health, and pathophysiologic analysis of related diseases with focus on neuroscience, immunology, metabolism, endocrine, reproduction, GI and liver. Faculty from basic and clinical sciences. Open to graduate students in biomedical science only.
INTD 574 Systems Biology and Disease Seminar (1, max 16, FaSp) Selected topics in systems biology and disease. Graded CR/NC. Open only to integrative biology of disease Ph.D. students.
INTD 620 Medical Students Elective Program (0) Opportunities for medical students as preceptors in research laboratories or in field medical service under guidance of sponsors approved by faculty committees. Graded CR/NC.
INTD 621ab Introduction to Clinical Medicine (ICM) for HTE (a: 3, Fa; b: 3, Sp) A strongly patient-centered course in which both Ph.D. engineering and M.D. students experience how doctors handle communications, basic diagnostic thinking and engineering perspectives. Open only to Health, Technology and Engineering students. Graded CR/NC.
INTD 622L Pre-clinical System Block for Health, Technology and Engineering (3-9, FaSp) A three-to-nine week block of lectures and laboratories focused on particular body system (e.g., cardiovascular, renal, etc.). Open only to Health, Technology and Engineering students. Graded CR/NC.
INTD 650 Stem Cell Biology and Medicine (4, FaSpSm) Basic principles, available embryonic and adult stem cells, principles of organogenesis and regeneration, animal models, delivery of engineered tissues to patients, promise and limitations of stem cells. Open to master’s and Ph.D. students on the Health Sciences Campus and to medical and post-doctoral fellow trainees only.