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Degrees and Requirements

The Keck School of Medicine and its departments offer types of curricula leading to award of the Doctor of Medicine, joint M.D./Ph.D., joint M.D./M.B.A. and graduate degrees in conjunction with the Graduate School in Applied Biostatistics/Epidemiology, M.S.; Biochemistry and Molecular Biology, M.S., Ph.D.; Biometry, M.S., Ph.D.; Biostatistics, M.S., Ph.D.; Cell and Neurobiology, M.S., Ph.D.; Clinical and Biomedical Investigations, M.S.; Epidemiology, Ph.D.; Experimental and Molecular Pathology, M.S.; Molecular Epidemiology, M.S., Ph.D.; Molecular Microbiology and Immunology, M.S., Ph.D.; Nurse Anesthesia, M.S.; Pathobiology, Ph.D.; Physiology and Biophysics, M.S., Ph.D.; Psychology and Public Health, Ph.D./M.P.H.; Statistical Genetics and Genetic Epidemiology, Ph.D.

The Department of Family Medicine offers the Master of Physician Assistant Practice. The Department of Preventive Medicine offers a B.S., Health Promotion and Disease Prevention Studies/Master of Public Health; Master of Public Health; Pharm.D./Master of Public Health; Ph.D., Physical Therapy/Master of Public Health; Ph.D., Preventive Medicine (Health Behavior Research); Ph.D. Statistical Genetics and Genetic Epidemiology; M.D./Master of Public Health; and minors in Health Communication, Nutrition and Health Promotion, Public Health and Substance Abuse Prevention.

In addition, departments of the school have certificate programs in certain medical specialties.

The Educational Policy Committee is responsible for overall planning of the medical school curriculum. Separate curriculum committees plan and supervise the instructional programs for each year of medical school. Each of the committees comprises student representatives and faculty members from the departments involved in each year's teaching program.

The curriculum of medical education at USC continues to emphasize preparation of the student to give optimal patient care. Students are progressively involved in patient care beginning with their first semester. The curriculum is patient-oriented, and students are expected to assume increasing responsibility for patient care as they acquire sufficient knowledge and skills. During the clinical experiences of the Junior/Senior Continuum students eventually attain a level equivalent to that of an intern.

At the same time, the school recognizes that the explosion of knowledge and techniques brought about by the current "biotechnology revolution" is rapidly altering the practice of medicine. During the four years of medical school, students cannot be taught all that will be needed for the practice of medicine -- either now or in the years ahead. To a far greater degree than in the past, the present curriculum encourages students to acquire skills and habits of self-education and self-instruction that will prepare them for lifelong learning.

The faculty of the school recognize that while most students will eventually practice medicine, some will choose an academic research career. The plan of medical education fosters the development of individuals whose careers may be directed along this path. Faculty are available to counsel and encourage research participation by students during their medical school training.

The curricula of the Keck School of Medicine and its departments acknowledge the crucial place of basic medical science in the advance of modern clinical practice. Both basic and clinical science are taught throughout the four years of the undergraduate medical curriculum. Basic science is taught both as pure basic science and in correlation with clinical science. In addition, a number of the school's departments cooperate with the USC Graduate School to offer degree courses leading to the award of the Master of Science and Doctor of Philosophy. Most of these graduate courses may also be taken as part of the school's joint M.D./Ph.D. program.

Doctor of Medicine

The Keck School of Medicine awards the Doctor of Medicine to enrolled students who have satisfactorily completed the four-year curriculum of the school. This curriculum integrates instruction in all departments of the school: Department of Anesthesiology, Department of Biochemistry and Molecular Biology, Department of Cell and Neurobiology, Department of Emergency Medicine, Department of Family Medicine, Division of Medical Education, Department of Medicine, Department of Molecular Microbiology and Immunology, Department of Neurological Surgery, Department of Neurology, Department of Obstetrics and Gynecology, Department of Ophthalmology, Department of Orthopaedics, Department of Otolaryngology -- Head and Neck Surgery, Department of Pathology, Department of Pediatrics, Department of Physiology and Biophysics, Department of Preventive Medicine, Department of Psychiatry and the Behavioral Sciences, Department of Radiation Oncology, Department of Radiology, Department of Surgery and Department of Urology.

The curriculum is designed to enhance the students' understanding of the basic sciences and their relevance to clinical medicine. The methodology used will improve students' problem-solving and independent study skills. Curriculum themes are delivered in a case-centered format with the integration of small-group learning sessions, directed independent study and newer instructional technologies emphasized.

The sections that follow provide a synopsis of the emphases and organization of this four-year curriculum.

Year I-II Continuum (two calendar years -- 76 weeks)

The first year of the Year I-II continuum begins with 19 weeks of Core Principles of Health and Disease followed by 49 weeks of organ system review ending with a nine-week Integrated Case Study section. There is an eight-week summer break between the first and second years. Students also take Introduction to Clinical Medicine and the Patient (described below).

Each week of the academic year is composed of approximately 20 hours of lecture and small group sessions with an additional 20 hours of independent directed study or Introduction to Clinical Medicine and the Patient. Examinations in all systems throughout the first two years are graded Pass/Fail. Dean's recognition is awarded on the basis of year-end comprehensive examinations and special projects.

Core Principles of Health and Disease
This 19-week introductory system provides the student with the fundamental knowledge necessary for the integrated study of the basic and clinical sciences in the 10 human organ systems. Included in this section are these major themes: cell structure and function; the human organism; disease and the body's responses; prevention and treatment of disease, including evidenced-based medicine; and introduction to clinical medicine and the patient. This section is taught in an integrated fashion and includes the use of clinical case studies.

Gross Anatomy
Cadaver dissection remains a unique teaching tool by which the three dimensional organization of the human body is studied. Gross anatomy will begin in the Core Principles of Health and Disease system continuing in the Hematology/Clinical Immunology system with the dissection of the body wall and major body cavities followed by head and neck dissection in the Neurosciences system and ending with limbs dissection during the Musculoskeletal system. Continued study of gross anatomy by use of prosected anatomical specimens as well as computer programs, selected review lectures, and so on, continues throughout the integrated organ systems.

Introduction to Clinical Medicine and the Patient (ICM)
ICM expresses the strongly patient-centered orientation of the medical school curriculum. The student is introduced to patients and is involved in patient care activities from day one. Students are introduced to the principles of patient care and management and examine what it means to be a physician and how one becomes a physician.

The major content areas of the course include communication in the setting of illness, the unified concept of health and disease (the biopsychosocial model), basic clinical skills and the correlation of basic science with clinical medicine.

ICM emphasizes the systematic acquisition of the clinical skills of interviewing, history taking, physical examination, elementary clinical problem solving, and medical record keeping. Throughout the Year I-II continuum, the ICM clinical skills curriculum is integrated with basic science instruction. Students can therefore learn and apply basic science knowledge in the clinical setting. By encouraging a thorough understanding of the direct applications of basic science research to modern clinical medicine, instructors motivate the student to learn, use and retain more of the content and concepts presented in the basic science portions of the curriculum.

A group of five or six students spends from four to eight hours each week with an instructor from the clinical faculty who remains with the group for one to two years. As the group deals with basic medical themes (death, pain and helplessness) and issues (patient responsibility, learning to live with ambiguity and uncertainty), instructors help students to cope with their own feelings. This format opens the door for student-faculty interaction and improvement of student-faculty communication.

Instructors encourage students to take advantage of the learning experiences provided by their roles as helping and therapeutic persons. Students develop their ability to communicate with patients in the setting of illness and are guided by patient concerns to enhance their own growing knowledge, skills, abilities and responsibilities. Students are expected to acquire skills and habits of self-education and self-instruction that will prepare them for lifelong learning.

The unified concept of health and disease presented in this course enables students to comprehend the human organism in all its complexity. Using their clinical experiences as a teaching model, students are taught to consider the patient as an integrated whole and to view the patient's illness or disease as more than simply a disruption of physiologic processes or a collection of physical findings.

Additional learning experiences occur through workshops and focus experiences. ICM workshops provide standardized instruction in history taking and physical examination, as well as integrated instruction in areas that cross disciplines. These include physician well being, substance abuse, domestic violence, and ethics. Through focus experiences, students are encouraged to explore a variety of practice environments as well as community-based health and social services. For example, students may visit outpatient clinical settings, a geriatrics long term care facility, a hospice care facility or homeless services organizations.

Organ System Review
A sequence of study presenting integrated basic and clinical science instruction involving 10 human organ systems -- Hematology and Clinical Immunology, Neurosciences, Musculoskeletal, Cardiovascular, Renal, Respiratory, Endocrine/Metabolism, Reproduction, Skin, Gastrointestinal/Liver -- follows Core Principles of Health and Disease.

Integrated Case Study
This section completes the second year of the Year I-II continuum and will emphasize patient-centered problems that integrate the basic and clinical science presented in the preceding organ systems. Students will explore the multi-organ effects of disease processes and reinforce diagnostic reasoning skills. In addition, concepts of pathophysiology, evaluation and management that can be applied to any organ system will be included. A review during this section of the important basic science and clinical concepts covered during the previous two years will prepare the students to take the United States Medical Licensing Examination (USMLE) Step 1 examination. This section will also reinforce the appropriate use of medical information resources, effective self-directed learning skills, and interpersonal and group communication skills.

By early spring of the second year of the Year I-II continuum, students are expected to select their academic clinical advisors and to begin arranging the schedule of clerkships to be taken during the junior/senior continuum. By the end of the fall semester, Year II, each student receives information that describes the curriculum requirements of the junior/senior continuum. Students choose the area of medical practice that they are most likely to pursue and an advisor is assigned from that discipline. The advisor counsels the student on clerkships and opportunities in graduate medical education.

Junior/Senior Continuum (two calendar years)

The final two years of medical school are designed as a continuum of two calendar years, beginning in July at the end of Year II. During the spring of their second year, students schedule clerkship rotations to be taken during the two years of the continuum. Each student's program is individually designed with the assistance of faculty advisors and includes 50 weeks of required clerkships, 12 weeks of selective clerkships and 18 weeks of elective clerkships.

All degree candidates are required to take Step I of the United States Medical Licensing Examination (USMLE) prior to entering the junior/senior continuum and pass it before starting their senior year of the continuum. Students must take Step II of the USMLE as a graduation requirement.

During the continuum each student may schedule 16 weeks of vacation for personal convenience, remedial work, funded research work and other non-curricular activities, such as investigating postgraduate training programs. Although every effort is made to provide flexibility in the scheduling of each student's program, some inherent limitations are imposed by the maximum enrollment permitted for each clerkship. Students are a vital part of the university's medical team, which provides health care for patients throughout the year. Vacations are therefore subject to some scheduling adjustments.

Required Clerkships

Family Medicine6 weeks
General Surgery/Specialty Surgery12 weeks
Medicine I6 weeks
Medicine II4 weeks
Neurology4 weeks
Obstetrics and Gynecology6 weeks
Pediatrics6 weeks
Psychiatry6 weeks

Selective Clerkships
Students are required to schedule 12 weeks of selective clerkships, chosen from a list of four- or six-week clerkships approved by the Clinical Curriculum Committee. Selective clerkships are carried out at USC-affiliated hospitals and encompass virtually all specialty areas.

Elective Clerkship
The elective period consists of 18 weeks, during which electives may be taken on campus, at USC-affiliated hospitals or at more distant medical schools or medical centers. Approved on-campus electives that are offered regularly are listed in the elective catalogue.

Proposals for other on-campus and off-campus electives are reviewed individually by a committee composed of faculty members and students. All petitions must be submitted at least six weeks before the beginning of the rotation. Off-campus electives require documentation from the off-campus preceptor, endorsement of the student's medical school advisor, and prior approval and review by the Clinical Curriculum Committee. Credit is not given for electives until an evaluation has been received from the preceptor and a critique of the elective submitted by the student. Students with an academic deficiency may not schedule off-campus electives.

From Bench to Bedside: Basic Science in the Practice of Medicine
The goals of this new required Year IV four-week course are to promote the use of basic scientific principles and knowledge in the everyday practice of medicine. Students obtain advanced instruction in laboratory medicine, molecular medicine and diagnostic imaging through use of clinical vignettes/PPP cases. All students attend and participate in an autopsy experience that includes instruction in indications for autopsy and completion of a death certificate. Students correlate autopsy and clinical findings and present a final report. At least half of the course time is spent completing one of several defined translational basic science projects (e.g., clinical anatomy review, evidence-based medicine literature review, surgical pathology or radiology). Students are evaluated by a written exam and by analysis of their autopsy presentation and project report.

Year I-IV -- Humanities, Economics, Art and the Law (HEAL)
This four-year curriculum begins with collaborative discourse about ethical problems to help students learn to identify, analyze and resolve clinical ethical problems. This exercise is followed by interim skill building/ maintenance and by instructor facilitated discussion of videotaped ethics cases.

In Year II, the program focuses on ethical discernment and action in simulated settings and the study of the human dimensions of medicine. In the first exercise, standardized patients interact with students to help teach the telling of bad news. Students also learn from the humanities about patients as persons. The program concludes with a forum theatre in which students must decide what action to take based on their own convictions.

Year III is devoted to ethics education by clinical role models and encompasses instruction in the core clerkship by ethical standard-bearers. Students also participate in home hospice care and pain management cases.

The Year IV program includes a series of retreats that focus on contemporary health care and the physician-in-society. The goal of the retreats is to provide students with the experience of integrating the principles, methods and bedside issues included in Year I-III of the program. Students practice applying the micro-level (individual/clinical) decisions to the ethical dilemmas and policy issues that face physicians at the mezzo-level (health care organizations), and to the macro-level (profession as a whole, state and nation). Topics include issues of professionalism; allocation of resources; the economics, organization and societal oversight of health care; and the care of dying patients.

Fifth Year Research Option
USC offers students the opportunity to take a full year of research experience with either a Keck School of Medicine faculty mentor or an approved faculty mentor at another institution. This program is open to any student in good to excellent academic standing who has completed his or her first year of medical school. Students interested in the option should identify a faculty preceptor and present a description of the proposed research program and funds available in support of the program to the associate dean for curriculum. A stipend, comparable to that received by a graduate student at the postgraduate level, is available. Application for this program is made through the Office for Curriculum (KAM 314) and will be supervised through the Office of the Associate Dean for Student Affairs (KAM 100E).

Baccalaureate/M.D. Program

The focus of this program is to assure these students admission to medical school (based upon the maintenance of their GPAs and requisite MCAT scores) and to allow them the opportunity to enrich their studies with a balanced liberal arts education. It is hoped that these students will explore the diverse educational opportunities the University of Southern California has to offer and become members of the medical profession with a balance of medicine, science and the arts. The Baccalaureate/M.D. Program is not designed to advance these potential medical professionals with four years of science and medicine prior to attending medical school, but rather to allow them the necessary time to explore and develop into mature and serious students of medicine.

Information and applications are available from the College Admissions Office, College of Letters, Arts and Sciences, University of Southern California, Los Angeles, CA 90089-0152; (213) 740-5930, FAX: (213) 740-1338.

M.D./Ph.D. Program

Departments of the Keck School of Medicine participate in the joint M.D./Ph.D. degree program administrated by the Graduate School and the Keck School of Medicine. This program integrates the medical school curriculum with graduate curricula in the basic sciences, to provide a unified course of study leading to both the M.D. and Ph.D. degrees.

This program is especially designed to prepare highly qualified students for careers in academic medicine and medical research. Formal course work and dissertation research provide the student with in-depth scientific preparation and research experience which enhances the application of basic science information to the diagnosis, treatment and prevention of disease. Conversely, the Ph.D. education becomes more meaningful because of its disease-oriented emphasis.

The curriculum for M.D./Ph.D. students differs from that of Ph.D. graduate students in the basic sciences in that the former take medical school courses as well as selected graduate level basic science courses. The integrated training of the M.D./Ph.D. program enables students to compress their total academic effort by applying some course work toward the requirements of both degrees. On average, completion of the combined program requires a total of eight years.

The following graduate programs at the Keck School of Medicine participate in the M.D./Ph.D. program:

  • Biochemistry and Molecular Biology
  • Cell and Neurobiology
  • Molecular Microbiology and Immunology
  • Pathology
  • Physiology and Biophysics
  • Preventive Medicine

Time limits for qualifying examinations and other procedures are determined by considering M.D./Ph.D. students as medical students for the periods when they are following the medical curriculum and as full-time graduate students during their years of graduate research prior to advancement to the Junior/Senior Continuum.

During the first two years of their program, M.D./Ph.D. students follow the medical school curriculum and gain added exposure to the basic science departments through a special survey course. Students are guided by the M.D./Ph.D. Committee, which outlines the integration of their graduate program with the medical school curriculum and serves as the students' liaison until they have selected a department and graduate research advisor. The graduate programs vary widely in the extent to which they allow credit toward the Ph.D. for courses taken during the first two years of medical school. M.D./Ph.D. students are encouraged to select a graduate department by January of the second year of medical school. Students will be required to apply for admission to the Ph.D. program by the deadline on the graduate application.

Beginning with the third year of the M.D./Ph.D. program, students enter their selected department as full-time graduate students. Although the content of graduate courses required of M.D./Ph.D. students is generally identical to that required of Ph.D. students in the same graduate program, M.D./Ph.D. students are permitted greater latitude in the scheduling of their graduate courses. Three years are commonly necessary to fulfill departmental requirements for the Ph.D., including course work, qualifying examinations, independent dissertation research, and writing of the dissertation.

After completion of the graduate program, the student is advanced to the Junior/Senior Continuum and completes the final two years of clinical training required by the medical school curriculum. No portion of clinical training is deleted from the joint program.

Keck School of Medicine-Caltech M.D./Ph.D. Program

A joint program between the Keck School of Medicine and the California Institute of Technology was established for the granting of the M.D./Ph.D. degree. Students do their preclinical and clinical work at the Keck School of Medicine and their Ph.D. work with any member of the Caltech faculty, including the biology, chemistry, engineering and applied sciences divisions.

Admission to this joint program is made through the usual Keck M.D./Ph.D. process. Following the interview at USC, a subset of applicants will be invited to interview at Caltech. An average of two students per year will be accepted into the joint program. Ph.D. studies may be carried out at Caltech or through collaboration between laboratories at both institutions. The M.D. degree will be awarded from the Keck School of Medicine and the Ph.D. from Caltech.

Further information about the M.D./Ph.D. programs at the Keck School of Medicine may be obtained by contacting: M.D./Ph.D. Program, Keck School of Medicine, 1975 Zonal Avenue (KAM 314), Los Angeles, CA 90033; (323) 442-2965, FAX: (323) 442-2318.

M.D./M.B.A. Dual Degree Program

In response to the ongoing reorganization of health care delivery systems, and the growing awareness of the impact of business decisions on health care, the Keck School of Medicine and the Marshall School of Business jointly offer an innovative program for individuals seeking knowledge in both medicine and business administration. The program is designed to prepare its graduates to assume leadership in the design and management of health care systems.

The M.D./M.B.A. program spans five-and-one-half years. Interested students apply during their second year of medical school, and begin core M.B.A. courses following successful completion of the first two years of medical school. The last two-and-one-half years are devoted to the clinical clerkships of the Keck School of Medicine and nine units of elective courses in the Marshall School. At the conclusion of the program, students will have completed 48 units in the Marshall School of Business and four years of courses in the Keck School of Medicine. Dual degree students may not count courses taken outside the Marshall School of Business toward the 48 units.

First and Second Years: Required medicine courses.

Third Year: Required M.B.A. core courses.

Remaining Two and One-Half Years: Keck School of Medicine core, selective, and elective clerkships and nine units of GSBA elective courses.

Admission Requirements
Students who have a baccalaureate degree from an accredited college or university and have successfully completed two years in the Keck School of Medicine will be considered for admission to the Marshall School of Business (see the Marshall M.B.A. Program section). All requirements for admission to the regular M.B.A. Program (GPA, GMAT score, etc.) must be fulfilled by the medical student for admission to the Marshall School.

The M.D. and the M.B.A. degrees are awarded simultaneously upon completion of their requirements by the Keck School of Medicine and the Marshall School of Business.

M.D./Master of Public Health

The joint M.D./M.P.H. program at the Keck School of Medicine is designed for individuals who envision a medical career that combines public health and medical disciplines. Many individuals entering careers as medical doctors or public health practitioners wish to acquire not only medical practice competencies, but also an understanding of the history, organization, goals and philosophy of public health. The joint M.D./M.P.H. program offers a broad-based orientation to public health while the student completes medical school requirements. The Master of Public Health degree provides increased knowledge of and sensitivity to the political, historical, economic and social environments of health promotion and health services delivery.

The M.D./M.P.H. program spans five years (four years of medical school and one year of public health courses). Students begin the core M.P.H. courses following the successful completion of the first two years of medical school. The last two years of the program are devoted to clinical clerkships of the School of Medicine and to the completion of the elective courses and practicum (field experience) of the M.P.H. program. At the conclusion of the joint degree program, students will have completed 42-46 units in the Master of Public Health program and four years of courses in the Keck School of Medicine.

Students who are enrolled in the Keck School of Medicine must apply to the Master of Public Health program no later than January of their second year. All requirements for admission to the regular M.P.H. program must also be fulfilled by dual degree applicants.

All students in the M.D./M.P.H. program must meet course requirements, grade point average requirements and program proficiency requirements of both programs. Students must have a grade point average of 3.0 in the M.P.H. curriculum to meet graduation requirements.

The M.D. and the M.P.H. degrees are awarded simultaneously upon completion of the Keck School of Medicine and the Master of Public Health program requirements. For more information, contact the M.P.H. Program Office at (626) 457-6677.

Ph.D. Programs in Biomedical and Biological Sciences (PIBBS)

Keith Administration Building 110
1975 Zonal Avenue
Los Angeles, CA 90089-9023
(323) 442-1609
FAX: (323) 442-1610
pibbs@usc.edu
www.usc.edu/pibbs

Program Director: Debbie Johnson

The USC Ph.D. Programs in Biomedical and Biological Sciences (PIBBS) offer opportunities for graduate studies and research leading to the Ph.D. degree in a broad range of biological and biomedical disciplines. Interdisciplinary studies that span multiple fields have sparked a startling surge in new discoveries that excite intellectually and also promise great benefits to society. The results will be a better understanding of our bodies and our environment.

Students admitted to the PIBBS programs spend two semesters taking courses in disciplines such as biochemistry, cell biology, molecular genetics and physiology; in addition, PIBBS students complete three or more research rotations in any of over 100 different research laboratories. Near the end of the second semester each student chooses a faculty member to serve as a thesis research advisor and chooses a specific Ph.D. program from among the participating programs listed. Subsequently, each student will focus on the completion of course requirements and qualifying examinations for the chosen Ph.D. program and will develop and complete an original research project that will serve as the basis for a doctoral dissertation.

For information on application materials and descriptions of the research interests of participating faculty, see the PIBBS site on USCweb.

Participating Schools and Graduate Programs

  • College of Letters, Arts and Sciences
    • Department of Biological Sciences
      • Marine and Environmental Biology
      • Molecular and Computational Biology
    • Neuroscience
  • School of Dentistry
    • Craniofacial Molecular Biology
    • School of Engineering Biomedical Engineering
  • Keck School of Medicine
    • Biochemistry and Molecular Biology
    • Cell and Neurobiology
    • Molecular Microbiology and Immunology
    • Pathobiology
    • Physiology and Biophysics
    • Preventive Medicine
      • Biostatistics, Epidemiology
  • School of Pharmacy
    • Molecular Pharmacology and Toxicology
    • Pharmaceutical Sciences

A detailed description of each of the Ph.D. programs listed here can be found by consulting the catalogue index.

Admission

Applicants to PIBBS must have a bachelor's or master's degree with a major emphasis in the natural sciences. Applicants must have a strong record of academic achievement, satisfactory performance on the general and advanced portions of the GREs and three letters of recommendation. Previous research experience in a related field is expected but not required. Students are admitted for the academic year beginning in the fall. Although there is no formal application deadline, complete applications received before January 15 will have a better chance of acceptance.

Applications and supporting materials should be sent to: PIBBS, University of Southern California, Office of Scientific Affairs, 1975 Zonal Avenue, KAM 110, Los Angeles, CA 90089-9023. Internet applications can also be submitted from the Web site.

Financial Support

Admitted students are supported by research assistantships or fellowships during their two semesters in the PIBBS program. Tuition, health insurance and standard fees are also covered. After the student completes the PIBBS program and enters a specific Ph.D. program, similar support mechanisms are generally provided by the Ph.D. granting program.

Curriculum

Most students will take the following courses during a two-semester period:

RequirementsUnits
BIOC 790Research
(taken in conjunction with the rotation plan described below)
1-12
INTD 504Molecular Biology of Cancer, or
INTD 555Biochemical and Molecular Bases of Disease, or
PHBI 562Systems and Integrative Physiology4
INTD 531Cell Biology4
INTD 561Molecular Genetics4
INTD 571Biochemistry4

However, the list of courses for individual students may vary from this plan with permission of the program director. As part of the BIOC 790 course, each student will complete research rotations with three or more faculty members in participating Ph.D. programs. Near the end of the second semester, each student will choose a faculty member to serve as dissertation advisor and will choose a specific Ph.D. program from the list of participating programs.

Graduate Degree Programs

In conjunction with the Graduate School, the Keck School of Medicine offers graduate curricula on the Health Sciences campus leading to the Doctor of Philosophy with majors in biochemistry and molecular biology, cell and neurobiology, molecular microbiology and immunology, pathobiology, physiology and biophysics.

The Departments of Preventive Medicine and Cell and Neurobiology along with the School of Policy, Planning, and Development offer the Master in Public Health with concentrated study in one of four tracks: health promotion and disease prevention, biostatistics/epidemiology, nutrition, and health communication.

The Department of Preventive Medicine also offers graduate curricula leading to Ph.D. degrees in biostatistics, epidemiology, or health behavior research.

Graduate credit is provided for some courses included in the Years I and II curriculum of the medical school.

The following sections provide an overview of the departmental graduate studies programs. The requirements listed are those of the individual departments and must be taken in conjunction with the general requirements of the Graduate School. For further information regarding graduate studies in the medical sciences, consult the specific departments or contact: Office of the Associate Dean for Scientific Affairs, Keck School of Medicine, 1975 Zonal Avenue (KAM 110), Los Angeles, CA 90089-9023; (323) 442-1607, FAX: (323) 442-1610.

Courses of Instruction

Interdepartmental (INTD)

The terms indicated are expected but are not guaranteed. For the courses offered during any given term, consult the Schedule of Classes.

462 Physiology for the Health Professions (4, Sp) (Enroll in PHBI 462)

500 Ethics and Accountability in Biomedical Research (1, Sm) The purpose of this course is to engage current (and potential) research trainees in discussions about the responsible conduct of science. The course is designed as an option for meeting current federal regulations which require that all predoctoral and postdoctoral fellows paid from federal contracts and grants have a component of ethical training.

504 Molecular Biology of Cancer (4) Epidemiology, pathobiology, carcinogenesis, tumor biology and heterogeneity; retroviruses, oncogenes, cell cycle control, genetics of cancer, tumor immunology; treatment strategies. Prerequisite: MICB 501.

504 Molecular Biology of Cancer (4, 2 years, Sp) Epidemiology, pathobiology, carcinogenesis, tumor biology and heterogeneity; retroviruses, oncogenes, cell cycle control, genetics of cancer, tumor immunology; treatment strategies. Prerequisite: MICB 501.

522 Infection and Host Responses (4, Sp) Overview of microbes, their life cycles and the host response they elicit, evade or exploit, including the manipulation and the malfunction of the immune system.

531 Cell Biology (4, Fa) Current perspectives on major research areas in cell biology. Emphasis will be on in-depth examination of cellular structures, regulatory processes, intra-cellular routing and targeting, and cell/environmental interactions.

535 Continuing Introduction to Clinical Medicine for M.D./Ph.D. Students (1, FaSp) Course for M.D./Ph.D. students in Ph.D. years designed to allow maintenance and improvement of clinical skills prior to re-entry in clinical rotations in the Year III medical curriculum. Open only to medical students who have completed Years I and II. Graded CR/NC.

549 Protein Chemistry -- Structure and Function (4, Sp) Chemistry of peptides and proteins; protein structure and folding; molecular basis of protein action. (Duplicates credit in former BIOC 549.) Prerequisite: general biochemistry.

550 Introduction to Pathology (6, Fa) Three separate series of lectures: one on normal histology, one on basic principles of microbiology, and the other on basic principles of immunology. Emphasis on normal aspects of biological processes important in disease pathogenesis. (Duplicates credit in former PATH 550aL.)

551 Advanced Pathology (6, Sp) Mechanisms of disease processes including inflammation, tissue injury and cell death, atherosclerosis, infectious diseases, diseases of the immune system, cancer, diseases of aging, and pollution. (Duplicates credit in former PATH 550bL.) Prerequisite: INTD 550.

555 Biochemical and Molecular Bases of Disease (4) Biochemical and molecular abnormalities in disease states. Prerequisite: general biochemistry.

561 Molecular Genetics (4, Sp) Prokaryotic and eukaryotic molecular genetics: DNA and RNA structure and function; biochemistry and molecular biology of replication, transcription, RNA processing, translation, and regulation of gene expression. (Duplicates credit in former BIOC 561.) Prerequisite: INTD 571.

562 Systems and Integrative Physiology (4) (Enroll in PHBI 562)

571 Biochemistry (4, Sp) Physical-chemical basis of life processes: protein structure and enzyme function; synthesis and metabolism of carbohydrates, lipids, amino acids, and nucleotides. (Duplicates credit in former BIOC 441.) Prerequisite: open to qualified students.

620 Medical Students Elective Program (0) Opportunities for medical students as preceptors in research laboratories or in field medical service under guidance of sponsors approved by faculty committees. Graded CR/NC.