MPTXPHARPMEPPSCI

Molecular Pharmacology and Toxicology (MPTX)

The terms indicated are expected but are not guaranteed. For the courses offered during any given term, consult the Schedule of Classes.

500 Molecular Pharmacology and Toxicology I (4, Fa) This is the first part of a two-semester introductory and survey course for the molecular pharmacology and toxicology degree program. Prerequisite: knowledge of biochemistry.

501 Molecular Pharmacology and Toxicology II (4, Sp) The second part of the two-semester course covers the general aspects of molecular pharmacology and toxicology on the basis of biochemical, molecular, biological and environmental approaches. Prerequisite: MPTX 500.

531 Cell Biology (4) (Enroll in INTD 531)

561 Molecular Genetics (4, Sp) (Enroll in INTD 561)

562 Systems and Integrative Physiology (4, Sp) (Enroll in PHBI 562)

571 Biochemistry (4, Fa) (Enroll in INTD 571)

594abz Master's Thesis (2-2-0, FaSpSm) Credit on acceptance of thesis. Graded IP/CR/NC.

599 Special Topics (2-4, max 8) Special topics in Molecular Pharmacology and Toxicology.

602 Science, Research and Ethics (2, Fa) A discussion of the unique technological and philosophical issues that challenge modern scientists and a discernment of ethical responses to those challenges.

603 Molecular Mechanisms for Biological Signals (4, Fa) Biological mechanisms of hormone, neuro-transmitter, growth factor and xenobiotic actions from ligand-receptor interactions, signal transductions, modification processes to regulation of gene expression and cellular growth. Prerequisite: knowledge of physiology and biochemistry.

605 Toxicology of Oxidants and Free Radicals (2, Sp) The chemistry, biochemistry, and physiology of oxygen and the biochemical mechanism of tissue-specific oxygen toxicity. Prerequisite: knowledge of biochemistry.

606 Pulmonary Toxicology (2, 2 years, Sp) Current concepts of inhalation toxicology and toxic mechanisms leading to lung injury. Lectures include basic pulmonary anatomy and physiology. Prerequisite: knowledge of biochemistry.

607 Special Topics in Molecular Pharmacology and Toxicology (2)

700 Seminar in Molecular Pharmacology and Toxicology (1, max 8, FaSp) Contemporary advances in molecular pharmacology and toxicology research. Registration required during each year of residency.

790 Research (1-12, FaSpSm) Research leading to the doctorate. Maximum units which may be applied to the degree to be determined by the department. Graded CR/NC.

794abcdz Doctoral Dissertation (2-2-2-2-0, FaSpSm) Credit on acceptance of dissertation. Graded IP/CR/NC.

Pharmacy (PHAR)

Course units published in the School of Pharmacy Bulletin 1996-1998 supersede those listed in this section only.

303 Pharmaceutics I (4, Fa) Introduction to physicochemical principles of dosage forms; properties of molecules in dosage forms, stability of pharmaceuticals and their interactions in body tissue, including computational approaches. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 303L.

306L Pharmaceutics II (4, Sp) Principles involved in molecules movement across biological barriers. Properties, characteristics, application of homogeneous and heterogeneous dosage forms, liquid, semi-solid and solid. Discussion and laboratory. Open to Doctor of Pharamcy students only. Duplicates credit in former PHAR 306L.

309 Biological Systems I (4, Fa) Integrated teaching of anatomy, histology, physiology and pathophysiology in organized sequence: cellular, skeletal, muscular, nervous and lymphatic systems. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 313 and PHAR 314.

310 Biological Systems II (6, Sp) Continued integration of anatomy, histology, physiology and pathophysiology: cardiovascular, respiratory, renal, gastrointestinal (digestive), endocrine, and reproduction systems. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 313 and PHAR 314.

315 Biochemistry (4, Fa) Chemical and molecular aspects of biological processes, including the chemistry of biomolecules, enzymology, bioenergetics, biochemical control mechanisms, and an introduction to metabolic diseases. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 315.

316 Molecular Genetics and Therapy (2, Sp) Principles of gene expression, and recombinant DNA methods and applications. Focus on human genetics and influence of genetic background on the utilization and effectiveness of specific drugs. Open to Doctor of Pharmacy students only.

319 Pharmacy Literature Review and Statistical Analysis (3, Fa) Literature evaluation and biostatistics of clinical and health services research, and epidemiology. Emphasis on the management of drug therapy products, patient outcomes and formulary development. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 332.

332 Over-the-Counter Pharmacy Products (3, Sp) Facilitate patient selection of self-care health care products: OTC drugs, their dosages, pharmacology, efficacy, cost, side effects, adverse reactions, contraindications, and interactions with other medications. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 331.

361 Introduction to Pharmaceutical Care Externship I (Hospital or Community) (1, Fa) Introduction of principles and the application of pharmaceutical care in community or hospital pharmacy setting. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 361.

362 Introduction to Pharmaceutical Care Externship II (Hospital or Community) (1, Sp) Continuation of Externship. At completion of this series, students will have had practical experience in pharmaceutical care in both community and hospital settings. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 362.

363 Communications Workshop (1, Fa) Development of communication skills to interact with other health care professionals, patients, and community members. Verbal/nonverbal communication is emphasized with specific reference to speaking, writing, listening. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 531.

365 Leadership and the Profession of Pharmacy (1, Fa) Development of leadership skills for the pharmacist in various pharmacy practice locations, in the community, and in professional societies and organizations. Open to Doctor of Pharmacy students only.

366 Statistics Laboratory (1, Sp) Development of relevant computational skills to collect, organize, validate and analyze data, display quantitative information graphically and visually, test statistical hypotheses and produce reports. Open to Doctor of Pharmacy students only.

368 Pharmaceutical Care Pharmacy Practice Lab I (1, Sp) Practical pharmaceutical calculations involving prescription interpretation, calculation of doses, reducing/enlarging formulas, specific gravity, percentage and ratio strength, dilution, isotonic solutions, electrolyte and parenteral solutions. Open to Doctor of Pharmacy students only.

403L Pharmaceutics III (4, Fa) Principles of absorption, distribution, metabolism, and elimination. Linear, non-linear, model-independent pharmacokinetics. Design of individualized dosing regimens and drug therapy monitoring. Lecture and discussion. Open to Doctor of Pharmacy students only.

406 Pharmaceutics IV (3, Sp) Principles and applications of controlled, targeted, and self-regulating drug delivery. Methods to deliver therapeutic peptides, proteins and genetic materials. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 406.

411L Clinical Microbiology (3, Fa) Pathobiology and epidemiology of microscopic organisms pathogenic to man including virus, bacteria, fungi, protozoa, helminths, and other selected "unclassified" microoganisms. Lecture and laboratory. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 411.

414 Therapeutics I (5, Sp) Integrated teaching of the biomedicinal chemistry, pharmacology, clinical pharmacokinetics, and therapeutics of drugs, with emphases on general principles, diagnostics, wellness and management of allergies. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 414, PHAR 420, PHAR 561.

418 Therapeutics II (4, Sp) Integrated teaching of the biomedicinal chemistry, pharmacology, clinical pharmacokinetics and therapeutics of drugs with emphasis on chemotherapy of infectious diseases: bacterial, microbial, viral, parasitic, fungal. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 412.

419 Pathology (3, Fa) Fundamental principles of pathophysiologic changes incident to abnormal states. Inflammation, infection, degeneration, regeneration and repair, neoplasia, and metabolic disturbances. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 318L.

422 Nutrition (2, Sp) Biomedical knowledge is correlated with assessments of clinical case-management problems to understand the interrelationship between nutrition and health in both hospitalized and healthy patients. Open to Doctor of Pharmacy students only.

432 Management within Health Care Organizations (2, Sp) Management of the professional practice of pharmacy in organized health care systems. Introduction to formulary development and outcome analysis. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 431.

437 Public Health and Epidemiology (3, Fa) Introduction to epidemiology, environmental health, health education, health care organizations and financing. Orientation to social and governmental controls on the health care system. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 437.

441 Immunology (3, Fa) Basic principles of immunology and their application to the understanding and treatment of immunologically-mediated diseases. Provides the scientific basis of immunotherapy and immunodiagnosis. Open to Doctor of Pharmacy students only.

450 Pharmaceutical Care Practice II (2, FaSp) Development of pharmacy clinical skills in physical assessment, microcomputer searching of the medical literature, drug information systems, and patient counseling. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 532, PHAR 564.

460 Parenteral Therapy Externship (2, FaSp) Drug weight/volume concentrations, dilutions and additive volumes are calculated in compounding of parenteral products in various patient-care settings using aseptic technique. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 460.

545 Therapeutics III (2, Fa) Integrated teaching of the biomedicinal chemistry, pharmacology, clinical pharmacokinetics, and therapeutics of drugs, with emphases on pharmaceuticals treating diseases associated with the autonomic nervous system. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 414, PHAR 420, PHAR 561.

546 Therapeutics VI (6, Sp) Integrated teaching of the biomedicinal chemistry, pharmacology, clinical pharmacokinetics, and therapeutics of drugs, with emphases on pharmaceuticals affecting cardiovascular and circulatory diseases. CPR certification. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 504, PHAR 514, PHAR 525, PHAR 562.

547 Therapeutics IV (6, Fa) Integrated teaching of the biomedicinal chemistry, pharmacology, clinical pharmacokinetics, and therapeutics of drugs, with emphases on pharmaceuticals treating diseases associated with the central nervous system. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 503, PHAR 513, PHAR 525, PHAR 561.

548 Therapeutics VII (3, Sp) Integrated teaching of the biomedicinal chemistry, pharmacology, clinical pharmacokinetics, and therapeutics of drugs, with emphases on treating diseases of the renal, GI and pulmonary systems. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 504, PHAR 514, PHAR 526, PHAR 562.

549 Therapeutics V (4, Fa) Integrated teaching of the biomedicinal chemistry, pharmacology, clinical pharmacokinetics, and therapeutics of drugs, with emphases on pharmaceuticals affecting the endocrine diseases, system and women's health. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 504, PHAR 514, PHAR 526, PHAR 564.

550 Therapeutics VIII (2, Sp) Integrated teaching of the biomedicinal chemistry, pharmacology, clinical pharmacokinetics and therapeutics of drugs, with emphases on pharmaceuticals for managing oncological, AIDS and immunological diseases. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 504, PHAR 514, PHAR 526, PHAR 562.

552 Pharmacy Law (2, Sp) Federal and state statutes, regulations and case law governing pharmacy practice including the laws that establish the standards for dangerous drugs and controlled substances. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 433.

553 Pharmaceutical Economics and Outcome Studies (3, Fa) Economic analysis of the U.S. health care system, the pharmaceutical industry, and the profession; economic assessment of drug therapy costs and health care outcomes applying pharmacoeconomic research methodologies. Open to Doctor of Pharmacy students only.

554 Pharmacy Ethics (2, Sp) Application of ethical principles to specific cases in medicine and pharmacy practice involving resolution of ethical dilemmas, consideration of the primary responsibility to the patient. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 433.

555 Community Pharmacy I (3, Fa) Development of specialized knowledge and skills in community pharmacy practice involving location analysis, pharmacy management principles, and introduction to business law concepts. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 440, PHAR 541.

556 Community Pharmacy II (3, Sp) A continuation of pharmacy business law concepts encompassing contract principles and forms of ownership, including a review of pharmacy laws, compounding principles, and OTC agents. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 542. Prerequisite: PHAR 555.

557 Health Systems Pharmacy I (3, Fa) Understanding formal and informal organizations in institutions, managed care, disease management, health care policy and financing, patients chart organization, and clinical monitoring parameters. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 440, PHAR 541.

558 Health System Pharmacy II (3, Sp) Recognizing resources available for drug information, familiarity with institutional formularies, medication counseling, writing chart notes, and clinical activities at an off-campus health care institution. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 542. Prerequisite: PHAR 557.

559 Geriatric Pharmacy I (3, Fa) Specialized knowledge and skills in geriatric pharmacy, pharmacology of aging, and unique functions of health care team providing care to the elderly patient. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 440, PHAR 541.

560 Geriatric Pharmacy II (3, Sp) Specialized knowledge and skills in gerontology and geriatric pharmacy including the pathophysiology of selected cardiovascular, endocrine, genitourinary, gastrointestinal disorders, osteoarthritis, and osteoporosis. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 542. Prerequisite: PHAR 559.

563 Computing Application (3, Fa) Specialized knowledge and skills using computers in professional practice: telecommunication protocols, typical patient databases in hospital and community pharmacies, drug interactions, insurance billing, inventory control. Open to Doctor of Pharmacy students only.

565 Basic Research Design (3, Fa) Research experience to integrate research into Doctor of Pharmacy program. Research focuses on industrial, academic, or governmental issues. Open to Doctor of Pharmacy students only.

566 Pharmaceutical Development (3, Sp) Examination of pharmaceutical product development process including discovery, preclinical/clinical studies, regulatory-legal issues, and marketing. Open to Doctor of Pharmacy students only.

568 Drugs of Abuse (3, Sp) Specialized knowledge and skills in specific substance abuse-related areas. Each area will include addiction, wellness, and prevention components. Open to Doctor of Pharmacy students only.

599 Special Topics (2-4, max 8)

601 Acute Care Clinical Practice Clerkship (6, FaSpSm) Application of pharmaceutical care principles to the adult patient population in an acute care environment. Pharmacology, pharmacokinetics, and disease state management will be emphasized. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 601.

602 Inpatient Psychopharmacy Clerkship (6, FaSpSm) Application of pharmaceutical care principles to the adult patient population in an acute care environment. Pharmacology, pharmacokinetics, and disease state management will be emphasized. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 602.

603 Skilled Nursing Facility Clerkship (6, FaSp) Learning experiences designed to develop competency in the safe and rational use of drugs. Opportunities to develop skills in benefiting patient care in the community.

604 Primary Care Clerkship (6, FaSpSm) Disease state management and pharmaceutical care in ambulatory care. Modification and design of drug therapy regimens, participation in medical care team and direct patient care. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 604.

605 Community Pharmacy Clerkship (4-6, FaSp) Placement in a community pharmacy. Involvement with the identification, planning, development, implementation, operation, and evaluation of specific patient care services.

606 Geriatrics Clerkship (4-6, FaSp) Drug therapy and management of geriatric patients with focus on unique medical, economic, and psychosocial problems of this population.

607 Outpatient Psychopharmacy Clerkship (6, FaSpSm) Disease state management and pharmaceutical care in ambulatory mental health care. Modification and design of psychiatric therapy regimens, participation in multidisciplinary teams and patient care. Open to Doctor of Pharmacy students only. Duplicates credit in former PHAR 604.

610 Inpatient Clinical Practice Clerkship (6, FaSp) Drug therapy in a variety of inpatient clinical settings. Emphasis: patient monitoring, evaluation of therapeutic response, and provision of drug information.

611 Pediatric Drug Therapy Clerkship (4-6, FaSp) Clinical therapeutic and pharmacokinetic concepts applied to the pediatric patient. Unique aspects of pediatric clinical pharmacology emphasized in treating a variety of organ system diseases.

612 Surgery Clerkship (4-6, FaSp) Drug therapy in clinical situations common to surgical patients. The use of drugs and monitoring response to drugs in surgical settings.

613 Cardiovascular Drug Therapy Clerkship (4-6) Use of cardiac drugs with emphasis on physiologic response, pharmacokinetic principles and practice.

614 Applied Clinical Pharmacokinetics Clerkship (4-6, FaSp) Practical experience in applying pharmacokinetic principles to patients with a variety of disease states.

615 Drug Information Services Clerkship (4-6, FaSp) Practical training in utilizing drug information resources to retrieve, organize, and solve health professional and patient drug therapy problems.

616 Radiopharmacy Clerkship (6, FaSp) Provides practical and theoretical aspects of radiopharmacy services delivery.

617 Oncology Clerkship (6, FaSp) Directed experiences in the use and monitoring of oncological drugs.

618 Ob-Gyn Clerkship (6, FaSp) Provides experiences in disease states common to this area and the drug therapy management employed.

619 Dermatology Clerkship (6) Provides experiences in disease states common to this area and the drug therapy management employed.

620 Community Hospital Pharmacy Practice Clerkship (4-6) Introduction to hospital pharmacy systems to maximize effective drug therapy. Emphasis on management and administrative skills.

621 Advanced Pharmaceutical Literature (2) Information sources and retrieval; scientific writing.

622 Current Therapy (4) Agents used in the diagnosis, prophylaxis, and treatment of various diseases. Lecture, 4 hours. Enrollment limited to hospital pharmacy residents and students with a prior degree in Pharmacy.

624 Critical Care Clerkship (6) Drug therapy in a critical care setting. Emphasizes therapeutic management in critically ill patients, often with multisystem failure.

625 Drug Utilization Evaluation Clerkship (4-6) Training in the design, implementation, and evaluation of appropriate and cost-effective drug therapy.

626 Home Health Care Clerkship (4-6) Practical experience in the provision of comprehensive home intravenous and nutritional support services, including fluid and electrolyte therapy, chemotherapy, antibiotics, and parenteral/enteral nutrition.

627 Nutritional Support Clerkship (4-6, FaSp) Experiential training in the pharmacy specialty of nutritional support. Activities include patient evaluation, generation of plan and consult, composition of formula, and integration with nutritional support team.

628 Advanced Community Pharmacy Clerkship (6, FaSp) Directed project in community pharmacy.

630abcd Directed Clinical Project (6-6-6-6, FaSp) Directed educational opportunities not presently offered as electives, e.g., research projects or new and evolving clerkships.

631 Acute Care Geriatrics Clerkship (4-6, FaSp) Drug therapy problem-solving in the acutely ill geriatric population, emphasizing physiology, pharmacokinetics and compliance problems.

632 Advanced Geriatrics Clerkship (6, FaSp) Directed projects and experiences in geriatric drug therapy.

633 Pharmacy Administration Clerkship (4-6, FaSp) Principles and practices of hospital pharmacy administration, management and departmental relationships.

634 Anticoagulation Therapy Clerkship (4-6, FaSp) Management of patients requiring anticoagulation. Applies knowledge of disease pathophysiology, anticoagulant pharmacology, and laboratory methods toward safe and effective anticoagulation.

635 Antimicrobial Therapy Clerkship (4-6, FaSp) Antimicrobial therapy, including antibiotic selection, dosage adjustment, and therapeutic evaluation.

636 Clinical Pharmacy Research Clerkship (4-6, FaSp) Drug research administration: research design; ethics; record-keeping; and institutional review.

637 Chemical Dependency (6, FaSp) The psychiatric, social, and pharmacological management of chemical dependency. Emphasizes the inpatient, day treatment, and outpatient components of detoxification and recovery.

638 Clinical Transplantation (6, FaSp) Drug therapy to organ transplantation. Emphasizes pre- and post-transplantation therapy designed to minimize organ rejection, prevent infection, and improve survival.

639 Pharmaceutical Industry (6, FaSp) Train within a pharmaceutical company to develop an understanding of the drug development, research, marketing process.

640 AIDS/Immune Disorders (6, FaSp) A multidisciplinary approach to the management of AIDS and other immuno-compromised patients. Pharmacologic management is directed toward opportunistic infections, disease modifiers, and adjuvant therapy.

641L Industrial Pharmacy (4) Preparation of tablets, capsules, injections, aerosols; utilizing techniques and equipment suitable for quantity production. Lecture, 3 hours; laboratory, 3 hours.

646 Clinical Pharmacology (4) Studies of drug actions and interactions in the patient in the hospital setting.

650 Clinical Pharmacology and Pathophysiology (4) Pathophysiology of diseases and drug induced pathological conditions.

Pharmaceutical Economics and Policy (PMEP)

538 Pharmaceutical Economics (4, Sp) Introduction to pharmacoeconomics with special emphasis on the role of pharmaceuticals and the pharmaceutical industry, insurance, managed care, regulation and pricing. Prerequisite: ECON 500.

539 Economic Assessment of Medical Care (4, Fa) Principles of cost-benefit analysis and medical cost-effectiveness analysis with applications in medical care and the pharmaceutical field. Prerequisite: ECON 500 and ECON 581.

540ab Seminar in Pharmaceutical Economics and Policy (2-2, Fa) This seminar will expand the student's understanding of fundamental techniques used in analyzing pharmaceutical policies and programs. Prerequisite: a: PMEP 538 and PMEP 539; b: PMEP 540a.

549 Applied Pharmacoeconometrics (4, Sp) Use of quantitative models to describe and analyze pharmaceutical and health care markets; experimental design/power calculations; survival models; multiple indicator models; qualitative and limited dependent variables models; estimation and application of such models to selected problems. Prerequisite: ECON 615.

698 Seminar in Pharmacuetical Economics and Policy (4, max 8, FaSp) Current research in pharmaceutical economics and policy presented by outside scholars, faculty and students. Graded CR/NC.

790 Research (1-12) Research leading to the doctorate. Maximum units which may be applied to the degree to be determined by the department. Graded CR/NC.

794abcdz Doctoral Dissertation (2-2-2-2-0) Credit on acceptance of dissertation. Graded IP/CR/NC.

Pharmaceutical Sciences (PSCI)

530 Biochemistry of Anti-Cancer Agents (2) (Enroll in BIOC 530)

531 Cell Biology (4) (Enroll in INTD 531)

561 Molecular Genetics (4, Sp) (Enroll in INTD 561)

562 Systems and Integrative Physiology (4, Sp) (Enroll in PHBI 562)

571 Biochemistry (4, Fa) (Enroll in INTD 571)

590 Directed Research (1-12, FaSpSm) Research leading to the master's degree. Maximum units which may be applied to the degree to be determined by the department. Graded CR/NC.

594abz Master's Thesis (2-2-0, FaSpSm) Credit on acceptance of thesis. Graded IP/CR/NC.

599 Special Topics (2-4, max 8, FaSp) Topics in advanced pharmaceutical sciences.

601 Molecular Biology of Gene Regulation (2, max 8) (Enroll in BIOC 601)

611L Chemical, Biological, and Pharmaceutical Aspects of Radionuclides (4) Synthesis, properties, and metabolism of labeled compounds of biological interest. Interaction of radiation with matter. Counting techniques. Radionuclides as pharmaceutical agents. Lecture and laboratory.

613L Radiobiology and Biological Effects of Radiation (4) Effects on the cellular level and on mammalian systems; their bearing on human exposure criteria. Lecture and laboratory.

652L Structure Activity Relationship and Drug Design (4, 2 years, Sp) Computerized correlation of biological activities with molecular structures and physico-chemical properties of drugs and their applications in designing new drugs. Lecture and laboratory.

653L Spectrometry in Biomedicine (4, 2 years, Fa) Theory of spectrometry and applications in pharmaceutical and biomedical sciences. Emphasis on structural identification of organic molecules, drugs and their metabolites of pharmaceutical interest. Lecture and laboratory.

654L Computer Applications in Pharmaceutical Sciences (3, 2 years, Fa) Introduction to computing facilities and computer applications frequently used in the study of pharmaceutical sciences. Students receive maximal hands-on exposure to computing.

655 Immunopharmaceutics (2, 2 years, Fa) Lectures and discussion sessions on pharmaceutics-related immunology, including drugs affecting the immune system, antibodies and cytokines as drugs, and new developments in immunobiotechnology.

661L Advanced Pharmaceutical Analysis (4, 2 years, Fa) Theory and application of quantitative instrumental techniques to the pharmaceutical sciences. Includes principles of chromatography, spectrophotometry, fluorescence, mass spectrometry and immunologic assays. Lecture and laboratory.

662 Advanced Pharmacokinetics (4, 2 years, Sp) Principles of pharmacokinetics including mathematical description of drug disposition processes. Emphasis on design and evaluation of pharmacokinetic studies and statistical analysis of parameter estimates.

663 Drug Dosage Form Design and Evaluation (4, 2 years, Fa) Principles of drug preformulation and formulation, principles and applications of controlled drug delivery and drug targeting.

671 Drug Morphology (3, 2 years, Fa) This course will examine drug metabolism in terms of hepatic and extrahepatic processes. Mechanisms of bioactivation and cellular toxicity will also be covered. Prerequisite: departmental approval.

756ab Seminar in Pharmaceutical Sciences (1-1, FaSpSm) Review of current pharmaceutical and related research topics.

790 Research (1-12, FaSpSm) Research leading to the doctorate. Maximum units which may be applied to the degree to be determined by the department. Graded CR/NC.

791L Research (2-12, no max) Directed research for the M.S. thesis or Ph.D. dissertation.

794abcdz Doctoral Dissertation (2-2-2-2-0, FaSpSm) Credit on acceptance of dissertation. Graded IP/CR/NC.

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