Courses of Instruction, page 2
School of Pharmacy

Pharmacy (PHAR)

303L Pharmaceutics I (5, Fa) Introduction to drug delivery systems. Physico-chemical properties of solutions, including functional group chemistry thermodynamic equilibria, and chemical kinetics. Principles of interfacial phenomena, rheology and radiopharmacy. Lecture and laboratory.

306L Pharmaceutics II (5, Sp) Principles of drug absorption, distribution, and elimination. Oral, nasal, pulmonary, rectal, vaginal, transdermal, ocular and parenteral dosage forms and their biopharmaceutics. Lecture and laboratory.

313 Anatomy and Histology (4, Fa) Macro and microanatomy of normal tissues following the organ system plan, enabling students to correlate form and function as background for subsequent work in the study of physiology and pharmacology.

314 Physiology (6, Sp) Functions and mechanisms of human organ systems as a background for the pharmacodynamics and disposition of drugs. Organ systems include endocrine, gastrointestinal, neuro-muscular, circulatory, respiratory, and renal.

315 Biochemistry (4, Fa) Chemical and molecular aspects of biological processes, including the chemistry and biomolecules, enzymology, bioenergetics, biochemical control mechanisms, and molecular genetics. Discussions on metabolic diseases and fundamentals of human nutrition.

318L Pathology (4, Sp) Fundamental principles of pathophysiologic changes incident to abnormal states. Inflammation, infection, degeneration, regeneration and repair, neoplasia, and metabolic disturbances. Lecture and laboratory.

331 Introduction to Pharmacy Practice and OTC Drugs (4, Fa) Survey of the profession, its structure and role in society and career options. Discussions on the contents and uses of non-prescription medication and development of skills in pharmacy calculations.

332 Literature Evaluation and Biostatistics (2, Sp) Introduction to literature evaluation and biostatistics as applied to clinical research, health services research, and pharmacy practice.

361 Practicum: Community or Hospital Pharmacy Externship I (1, Fa) Experience in drug distribution, management techniques, record keeping, provision of drug information, government regulations, communication skills. Pharmacy practice in community or hospital pharmacy setting.

362 Practicum: Community or Hospital Externship II (1, Sp) Continuation of Community or Hospital Pharmacy Externship I. At completion of this series, students will have had practical experience in both the community and hospital pharmacy settings.

371x Clinical Pharmacy and Therapeutics I (6, Fa) Fundamental principles and skills for clinical management and evaluation of drug therapy; pathophysiology of diseases, clinical pharmacology, and pharmacokinetics. Lecture and case study discussions. Not available for credit toward the Pharm.D.

372x Clinical Pharmacy and Therapeutics II (6, Sp) Continuation of 371x. Lecture and case study discussions. Not available for credit toward the Pharm.D.

373x Clinical Pharmacy and Therapeutics III (6, Sm) Continuation of 372x. Lecture and case study discussions. Not available for credit toward the Pharm.D.

390 Special Problems (1-4) Supervised, individual studies. No more than one registration permitted. Enrollment by petition only.

403L Pharmaceutics III (4, Fa) Principles of pharmacokinetics and drug metabolism, including modeling of drug disposition, calculation of dosage regimens and therapeutic drug monitoring. Lecture and laboratory.

406 Pharmaceutics IV (4, Sp) Principles and applications of controlled, targeted, and self-regulating drug delivery. Methods to deliver therapeutic peptides, proteins and genetic materials. Immunopharmaceutics.

411L Microbiology (4, Fa) Basic principles of bacteriology, pathogenesis, host defense mechanisms, chemotherapy, immunotherapy, sterilization and disinfection; specific microbial agents of disease: bacteria, virus, fungi and parasites. Lecture and laboratory.

412 Antimicrobial Agents (4, Sp) Chemical, pharmacologic and pharmacokinetic properties, clinical indications, dosage forms, administration, toxicities and drug interactions of antimicrobial agents; chemotherapy of selected infectious diseases.

414 Pharmacology I (3, Sp) Introduction to principles of drug action and the pharmacology of drugs affecting the peripheral nervous system. Topics include drug-receptor interactions, drug toxicity, and pharmacological basis of therapeutics.

420 Biomedicinal Chemistry I (3, Sp) Introduction to the biomedicinal chemistry of natural and synthetic drugs including organic nomenclature, receptor classification, and natural products overview.

431 Management Concepts in Pharmacy (3, Fa) Management of the professional practice of pharmacy in community, hospital, and institutional settings; introduction to finance, marketing, operations, and personnel administration.

433 Pharmacy Jurisprudence and Professional Ethics (3, Fa) Federal and state laws and regulations governing pharmacy practice, including dangerous drugs and controlled substances. Standards of practice of the profession and ethical behavior issues.

437 Public Health and Social Pharmacy (2, Fa) Introduction to epidemiology, environmental health, health education, health care organizations and financing. Orientation to social and governmental controls on the health care system.

439 Health Behavior (2, Fa) Overview of lifestyles related to the major causes of mortality and morbidity. Strategies for modification of health-related behavior; behavioral medicine and alternative therapies.

440 Track I (2, Sp) Presentation of a practice-oriented or discipline-specific continuum of material such as community pharmacy, hospital pharmacy, or geriatrics.

460 Practicum: Parenteral Drug Therapy (2, Sp) Experience in preparation, stability, and use of intravenous solutions. Develops skills in aseptic technique, quality control and monitoring of selected intravenous therapies.

503 Pharmaceutics V (2, Fa) Pharmacokinetic properties and therapeutic drug monitoring considerations for a variety of drug classes in conjunction with discussions of their pharmacology and biomedicinal chemistry.

504 Pharmaceutics VI (2, Sp) Continuation of Pharmaceutics V with discussion of pharmacokinetic properties and therapeutic drug monitoring considerations for a variety of drug classes.

513 Pharmacology II (3, Fa) Continuation of Pharmacology I, emphasizing drugs affecting the central nervous and cardiovascular systems. Topics include general anesthetics, sedative-hypnotics, analgesics, anxiolytics, antidepressants, antipsychotics and antihypertensives.

514 Pharmacology III (3, Sp) Continuation of Pharmacology II with emphasis on pharmacology and therapeutic use of drugs affecting cardiovascular, renal and endocrine systems and inflammatory and neoplastic diseases.

525 Biomedicinal Chemistry II (3, Fa) Continuation of Biomedicinal Chemistry I with emphasis on chemistry of drugs affecting the central nervous and cardiovascular systems. Lectures are correlated with discussions of pharmacologic and pharmacokinetic properties of drugs.

526 Biomedicinal Chemistry III (3, Sp) Continuation of Biomedicinal Chemistry II with emphasis on drugs affecting renal and endocrine systems. Topics include compounds used in treating inflammatory and neoplastic diseases.

531 Principles of Professional Communication (3, Fa) Emphasis on interpersonal and organizational communication with special attention to the written, oral, and listening skills required in community pharmacy, hospital pharmacy and related settings.

532 Professional Interactions (2, Sp) Skills in interviewing, understanding, and counseling patients in context of their illness or disease states. Lecture and supervised training in small groups.

541 Track II (2, Fa) Continuation of Track I with emphasis on practice-oriented information.

542 Track III (2, Sp) Continuation of Track II with emphasis on practice-oriented information.

551 Contemporary Issues (1, Fa) Faculty and invited speakers present topics of current interest related to biomedical sciences, health care delivery systems, national health policy, and contemporary practices in pharmacy.

561 Clinical Therapeutics I (4, Fa) Pathophysiology of disease states and therapeutic modalities in treatment. Discussions focus on drug therapy monitoring skills. Course integrated with pharmacology, pharmacokinetics, and biomedicinal chemistry.

562 Clinical Therapeutics II (4, Sp) Continuation of Clinical Therapeutics I. Discussions related to pathophysiology of disease and therapeutic modalities. Lectures, case studies integrated with pharmacology, pharmacokinetics, biomedicinal chemistry, and communication.

564 Clinical Skills (2, Sp) Didactic and practical experience in physical assessment and patient evaluation skills, the use of durable goods, and disposable monitoring supplies. Students receive CPR certification.

599 Special Topics (2-4, max 8)

601 Drug Therapy in Acute Care Medicine Clerkship (4-6, FaSp) Clinical therapeutic and pharmacokinetic concepts applied to the adult patient. Applied clinical pharmacology emphasized in treating a variety of organ system diseases.

602 Psychopharmacy Clerkship (4-6, FaSp) Clinical training in mental health pharmacy practice with emphasis on interviewing techniques and patient education. Includes a multidisciplinary approach to optimizing psychotropic drug therapy.

603 Skilled Nursing Facility Clerkship (6, FaSp) Learning experiences designed to develop competency in the safe and rational use of drugs. Opportunities to develop skills in benefiting patient care in the community.

604 Ambulatory Care Clerkship (4-6, FaSp) Clinical skills in drug monitoring and patient evaluation necessary to function as a member of the ambulatory health care team.

605 Community Pharmacy Clerkship (4-6, FaSp) Placement in a community pharmacy. Involvement with the identification, planning, development, implementation, operation, and evaluation of specific patient care services.

606 Geriatrics Clerkship (4-6, FaSp) Drug therapy and management of geriatric patients with focus on unique medical, economic, and psychosocial problems of this population.

610 Inpatient Clinical Practice Clerkship (6, FaSp) Drug therapy in a variety of inpatient clinical settings. Emphasis: patient monitoring, evaluation of therapeutic response, and provision of drug information.

611 Pediatric Drug Therapy Clerkship (4-6, FaSp) Clinical therapeutic and pharmacokinetic concepts applied to the pediatric patient. Unique aspects of pediatric clinical pharmacology emphasized in treating a variety of organ system diseases.

612 Surgery Clerkship (4-6, FaSp) Drug therapy in clinical situations common to surgical patients. The use of drugs and monitoring response to drugs in surgical settings.

613 Cardiovascular Drug Therapy Clerkship (4-6) Use of cardiac drugs with emphasis on physiologic response, pharmacokinetic principles and practice.

614 Applied Clinical Pharmacokinetics Clerkship (4-6, FaSp) Practical experience in applying pharmacokinetic principles to patients with a variety of disease states.

615 Drug Information Services Clerkship (4-6, FaSp) Practical training in utilizing drug information resources to retrieve, organize, and solve health professional and patient drug therapy problems.

616 Radiopharmacy Clerkship (6, FaSp) Provides practical and theoretical aspects of radiopharmacy services delivery.

617 Oncology Clerkship (6, FaSp) Directed experiences in the use and monitoring of oncological drugs.

618 Ob-Gyn Clerkship (6, FaSp) Provides experiences in disease states common to this area and the drug therapy management employed.

619 Dermatology Clerkship (6) Provides experiences in disease states common to this area and the drug therapy management employed.

620 Community Hospital Pharmacy Practice Clerkship (4-6) Introduction to hospital pharmacy systems to maximize effective drug therapy. Emphasis on management and administrative skills.

621 Advanced Pharmaceutical Literature (2) Information sources and retrieval; scientific writing.

622 Current Therapy (4) Agents used in the diagnosis, prophylaxis, and treatment of various diseases. Lecture, 4 hours. Enrollment limited to hospital pharmacy residents and students with a prior degree in Pharmacy.

624 Critical Care Clerkship (6) Drug therapy in a critical care setting. Emphasizes therapeutic management in critically ill patients, often with multisystem failure.

625 Drug Utilization Evaluation Clerkship (4-6) Training in the design, implementation, and evaluation of appropriate and cost-effective drug therapy.

626 Home Health Care Clerkship (4-6) Practical experience in the provision of comprehensive home intravenous and nutritional support services, including fluid and electrolyte therapy, chemotherapy, antibiotics, and parenteral/enteral nutrition.

627 Nutritional Support Clerkship (4-6, FaSp) Experiential training in the pharmacy specialty of nutritional support. Activities include patient evaluation, generation of plan and consult, composition of formula, and integration with nutritional support team.

628 Advanced Community Pharmacy Clerkship (6, FaSp) Directed project in community pharmacy.

630abcd Directed Clinical Project (6-6-6-6, FaSp) Directed educational opportunities not presently offered as electives, e.g., research projects or new and evolving clerkships.

631 Acute Care Geriatrics Clerkship (4-6, FaSp) Drug therapy problem-solving in the acutely ill geriatric population, emphasizing physiology, pharmacokinetics and compliance problems.

632 Advanced Geriatrics Clerkship (6, FaSp) Directed projects and experiences in geriatric drug therapy.

633 Pharmacy Administration Clerkship (4-6, FaSp) Principles and practices of hospital pharmacy administration, management and departmental relationships.

634 Anticoagulation Therapy Clerkship (4-6, FaSp) Management of patients requiring anticoagulation. Applies knowledge of disease pathophysiology, anticoagulant pharmacology, and laboratory methods toward safe and effective anticoagulation.

635 Antimicrobial Therapy Clerkship (4-6, FaSp) Antimicrobial therapy, including antibiotic selection, dosage adjustment, and therapeutic evaluation.

636 Clinical Pharmacy Research Clerkship (4-6, FaSp) Drug research administration: research design; ethics; record-keeping; and institutional review.

637 Chemical Dependency (6, FaSp) The psychiatric, social, and pharmacological management of chemical dependency. Emphasizes the inpatient, day treatment, and outpatient components of detoxification and recovery.

638 Clinical Transplantation (6, FaSp) Drug therapy to organ transplantation. Emphasizes pre- and post-transplantation therapy designed to minimize organ rejection, prevent infection, and improve survival.

639 Pharmaceutical Industry (6, FaSp) Train within a pharmaceutical company to develop an understanding of the drug development, research, marketing process.

640 AIDS/Immune Disorders (6, FaSp) A multidisciplinary approach to the management of AIDS and other immuno-compromised patients. Pharmacologic management is directed toward opportunistic infections, disease modifiers, and adjuvant therapy.

641L Industrial Pharmacy (4) Preparation of tablets, capsules, injections, aerosols; utilizing techniques and equipment suitable for quantity production. Lecture, 3 hours; laboratory, 3 hours.

646 Clinical Pharmacology (4) Studies of drug actions and interactions in the patient in the hospital setting.

650 Clinical Pharmacology and Pathophysiology (4) Pathophysiology of diseases and drug induced pathological conditions.

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Produced by the USC Division of Student Affairs, Office of University Publications, May 1, 1995
David Henriquez
univpub@stuaff.usc.edu