502ab Molecular Genetics and Biochemistry (4-4, FaSp) Current genetic and biochemical analysis of replication, recombination, mutagenesis, and repair. Fundamentals of transcription and regulation of gene expression. Recent applications of genetic engineering and genome analysis.

504L Laboratory Techniques in Cellular and Molecular Biology (1- 4, max 8, FaSp) Rotation of graduate students through Molecular Biology research laboratories to learn the major technological skills required in the field. Graded CR/NC.

505 Genomics and Molecular Genetics (4, Sp) Molecular genetics (mutagenesis, repair, recombination, and gene regulation) from quantitative and mechanistic approaches. Simple and complex genome analysis using recombinant DNA, physical, and computational techniques. Recommended preparation: BISC 502b.

506 Physical Chemical Principles of Cellular and Molecular Biology (4, Fa) Equilibrium and steady-state systems in biology. Debye-Huckel theory; diffusion, viscous flow, electrophoresis, sedimentation; optical refraction, absorption, scattering, diffraction, rotation by biopolymers. Prerequisite: general biochemistry; mathematics through calculus.

507 Advanced Molecular Biology: Prokaryotes (1, Fa) Discussion accompanying BISC 402. Concurrent registration in BISC 402 is required of graduate students. Two hours. (Duplicates credit in former BISC 541a)

508 Advanced Molecular Biology: Eukaryotes (1, Sp) Discussion accompanying BISC 403. Concurrent registration in BISC 403 is required of graduate students. Two hours. (Duplicates credit in former BISC 541b)

509L Advanced Invertebrate Zoology (4) Study of selected organ systems of marine invertebrates with emphasis on comparative anatomy and functional morphology with reference to behavior and ecology. Lecture, 3 hours; laboratory, 3 hours.

518 Recent Advances in Cellular and Molecular Biology (2 or 4, max 12, FaSp) Lectures on cellular and molecular biology. Registration restricted to three semesters.

520 Recent Advances in Neurobiology (2 or 4, max 12, Fa) Lectures on selected topics in neurobiology. Registration restricted to three semesters. Prerequisite: graduate status in departmental program or departmental approval.

524 Advanced Neurosciences I (4, Fa) Nervous system anatomy, electrophysiology, molecular biology, pharmacology. Prerequisite: BISC 421. (Duplicates credit in former BISC 525a)

525 Advanced Neurosciences II (4, Sp) Development, plasticity, sensorimotor integration, neuroendocrinology, and computational neurobiology. Prerequisite: BISC 421. (Duplicates credit in former BISC 525b)

527 Mammalian Neuroanatomy (4) Major functional systems of the mammalian nervous system are reviewed; overview of development, histology, and research techniques. Prerequisite: BISC 524 and BISC 525 or departmental approval.

529 Seminar in Marine Biology (1, max 4, FaSp) Graded CR/NC.

530 Seminar (2, max 8, FaSp)

531 Seminar in Marine Invertebrate Zoology (2, max 8, FaSp)

532 Seminar in Ecology (2, max 8, FaSp)

535 Seminar in Physiology (2, max 8, FaSp)

537 Seminar in Cellular and Molecular Biology (2, max 8, FaSp)

539 Seminar in Neurobiology (1, max 4, FaSp)

540 Seminar in Biogeography (2, max 8)

542 Seminar in Molecular Biology (1, max 6, FaSp) Graded CR/NC.

549L Bioelectronics (4, Irregular) Theory of measuring electrical signals from biological tissues; analysis and design of circuits commonly used in physiological studies; analogue and digital electronics; integrated circuits. Lecture, 2 hours; discussion, 2 hours; laboratory, 3 hours.

551 Biosystematics (4) Philosophies of classification of organisms; their use in biological theory and practice.

553 Biogeography (4, Irregular) Geographic distribution of plants and animals; patterns of vicariance, radiation and dispersal; major biotic regions, ecological and historical causal factors; construction of biogeography theory.

554 Models in Ecological Research (4, Irregular) Lectures and seminars on the utility of conceptual, analog, mechanistic modeling; the use of microcosms in ecological research. Independent project required. Basic computer experience recommended.

568 Functional Morphology of Marine Organisms (4, Irregular) Advanced functional analyses of specific organ systems and life processes in selected major taxonomic groups of marine animals.

573L Marine Ecology (4, Irregular) Interrelationships between marine populations and communities and their environments. Lecture, 2 hours; laboratory, 6 hours. Recommended preparation: elementary course in statistics.

581L Current Problems in Marine Sciences (4, max 16, Irregular) In-depth studies on selected problems of current interest in the marine sciences. Lecture and laboratory.

582 Advanced Biological Oceanography (4, Fa) Aspects of physics and chemistry of the oceans. Qualitative and quantitative considerations of the ecology of pelagic and benthic communities.

583 Biochemistry and Physiology of Marine Organisms (4, Fa) Biochemical and physiological adaptations of marine bacteria, plants, and animals to the wide range of environments that exists in the ocean.

586L Developmental Biology of Marine Organisms (4, Sp) Descriptive and experimental studies of developmental stages of marine plants and animals; patterns of reproductive biology; larval biology; metamorphosis.

590 Directed Research (1-12, FaSpSm) Research leading to the master's degree. Maximum units which may be applied to the degree to be determined by the department. Graded CR/NC.

599 Special Topics (2-4, max 8, Irregular)

790 Research (1-12, FaSpSm) Research leading to the doctorate. Maximum units which may be applied to the degree to be determined by the department. Graded CR/NC.

794abcdz Doctoral Dissertation (2-2-2-2-0, FaSpSm) Credit on acceptance of dissertation. Graded IP/CR/NC.

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